Prologue: The Search for Innovative Learning -- Introduction. Learning to Innovate, Innovating Learning -- Pt. 1. What Is 21st Century Learning? -- 1. Learning Past and Future -- 2. The Perfect Learning Storm: Four Converging Forces -- Pt. 2. What Are 21st Century Skills? -- 3. Learning and Innovation Skills: Learning to Create Together -- 4. Digital Literacy Skills: Info-Savvy, Media-Fluent, Tech-Tuned -- 5. Career and Life Skills: Work-Ready, Prepared for Life -- Pt. 3. 21st Century Learning in Practice -- 6. 21st Century Learning and Teaching -- 7. Powerful Learning: Proven Practices, Researched Results -- 8. Retooling Schooling: Reshaping Support Systems -- 9. Conclusion: Learning for Life - Building a Better World -- App. A. Resources -- App. B. About the Partnership for 21st Century Skills -- App. C. 3Rs x 7Cs = 21st Century Learning.