1. Introduction -- 2. Communication and Collaboration in Interdisciplinary Research -- Part I Theory -- 3. Communicating Complex Concepts -- 4. Training the Next Generation of Transdisciplinarians -- 5. Beyond Common Ground: A Transdisciplinary Approach to Interdisciplinary Communication and Collaboration -- 6. Interdisciplinarity, Communication, and the Limits of Knowledge -- Part II Case Studies -- 7. Rising to the Synthesis Challenge in Large-Program Interdisciplinary Science: The QUEST Experience -- 8. Enhancing Interdisciplinary Communication: Collaborative Engaged Research on Food Systems for Health and Well-Being -- 9. Discourse Communities, Disconnects, and Digital Media: The Case of Relocalizing Economies for Sustainable Agriculture and Energy Systems -- 10. Conceptual Barriers to Interdisciplinary Communication: When Does Ambiguity Matter? -- Part III Tools -- 11. Seeing Through the Eyes of Collaborators: Using Toolbox Workshops to Enhance Cross-Disciplinary Communcations -- 12. Integration of Frameworks and Theories Across Disciplines for Effective Cross-Disciplinary Communication -- 13. Modeling as a Tool for Cross-Disciplinary Communication in Solving Environmental Problems -- Part IV Contexts -- 14. Interdisciplinarity as a Design Problem: Toward Mutual Intelligibility Among Acedemic Disciplines in the American Research University -- 15. Defining 21st Century Land-Grant Universities Through Cross-Disciplinary Research -- 16. Institutionalizing Interdisciplinary Graduate Education -- 17. Supporting Interdisciplinary Collaboration: The Role of the Institution -- Part V Conclusion -- 18. From Toolbox to Big Science Project: A Bold Proposal.